A Sequential Model of Host Cell Killing and Phagocytosis byEntamoeba histolytica | Zendy

Adam Sateriale | Zendy; Christopher D. Huston | Zendy

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A Sequential Model of Host Cell Killing and Phagocytosis byEntamoeba histolytica

Author(s) -

Adam Sateriale,

Christopher D. Huston

Publication year - 2011

Publication title -

journal of parasitology research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.46

H-Index - 27

eISSN - 2090-0031

pISSN - 2090-0023

DOI - 10.1155/2011/926706

Subject(s) - entamoeba histolytica , phagocytosis , virulence , cytolysis , microbiology and biotechnology , context (archaeology) , entamoeba , biology , parasite hosting , host (biology) , virology , cytotoxicity , gene , computer science , in vitro , genetics , world wide web , paleontology

The protozoan parasite Entamoeba histolytica is responsible for invasive intestinal and extraintestinal amebiasis. The virulence of Entamoeba histolytica is strongly correlated with the parasite's capacity to effectively kill and phagocytose host cells. The process by which host cells are killed and phagocytosed follows a sequential model of adherence, cell killing, initiation of phagocytosis, and engulfment. This paper presents recent advances in the cytolytic and phagocytic processes of Entamoeba histolytica in context of the sequential model.

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