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Low- and High-Tech Approaches to ControlPlasmodiumParasite Transmission byAnophelesMosquitoes
Author(s) -
Chris M. Cirimotich,
April M. Clayton,
George Dimopoulos
Publication year - 2011
Publication title -
journal of tropical medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.747
H-Index - 30
eISSN - 1687-9694
pISSN - 1687-9686
DOI - 10.1155/2011/891342
Subject(s) - malaria , anopheles , plasmodium (life cycle) , transmission (telecommunications) , biology , parasite hosting , plasmodium falciparum , mosquito control , virology , immunology , computer science , telecommunications , world wide web
Current efforts have proven inadequate to stop the transmission of Plasmodium parasites, and hence the spread of malaria, by Anopheles mosquitoes. Therefore, a novel arsenal of strategies for inhibiting Plasmodium infection of mosquitoes is urgently needed. In this paper, we summarize research on two approaches to malaria control, a low-tech strategy based on parasite inhibition by the mosquito's natural microflora, and a high-tech strategy using genetic modification of mosquitoes that renders them resistant to infection and discuss advantages and disadvantages for both approaches.

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