Open AccessP2O5/SiO2 as a New, Efficient and Reusable Catalyst for Preparation of 4,4′‐Epoxydicoumarins Under Solvent‐free Conditions
Author(s) -
Liqiang Wu,
Xiao Wang
Publication year - 2011
Publication title -
journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2090-9063
pISSN - 2090-9071
DOI - 10.1155/2011/849795
Subject(s) - chemistry , catalysis , phosphorus pentoxide , environmentally friendly , solvent , organic chemistry , phosphorus , chemical engineering , engineering , ecology , biology
An efficient solvent-free procedure for the preparation of 4,4′-epoxydicoumarins via the ondensation of 4-hydroxycoumarin with aldehydes in the presence of catalytic amount of phosphorus pentoxide/silica gel at 110 °C is described. The advantages of this method are generality, high yields, short reaction times, ease of product isolation, low cost and ecologically friendly.
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