An Efficient Therapy Strategy under a Novel HIV Model | Zendy

Chunming Zhang | Zendy; Xiaofan Yang | Zendy; Wanping Liu | Zendy; LuXing Yang | Zendy

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An Efficient Therapy Strategy under a Novel HIV Model

Author(s) -

Chunming Zhang,

Xiaofan Yang,

Wanping Liu,

LuXing Yang

Publication year - 2011

Publication title -

discrete dynamics in nature and society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.264

H-Index - 39

eISSN - 1607-887X

pISSN - 1026-0226

DOI - 10.1155/2011/828509

Subject(s) - human immunodeficiency virus (hiv) , context (archaeology) , computer science , control (management) , virus , virology , medicine , artificial intelligence , biology , paleontology

By incorporating the chemotherapy into a previous model describing the interaction of the immune system with the human immunodeficiency virus (HIV), this paper proposes a novel HIV virus spread model with control variables. Our goal is to maximize the number of healthy cells and, meanwhile, to minimize the cost of chemotherapy. In this context, the existence of an optimal control is proved. Experimental results show that, under this model, the spread of HIV virus can be controlled effectively

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