Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients | Zendy

Krista A. DelviksFrankenberry | Zendy; Chawaree Chaipan | Zendy; Rachel Bagni | Zendy; Kathleen M. Wyvill | Zendy; Robert Yarchoan | Zendy; Vinay K. Pathak | Zendy

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Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients

Author(s) -

Krista A. DelviksFrankenberry,

Chawaree Chaipan,

Rachel Bagni,

Kathleen M. Wyvill,

Robert Yarchoan,

Vinay K. Pathak

Publication year - 2011

Publication title -

advances in virology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.956

H-Index - 25

eISSN - 1687-8647

pISSN - 1687-8639

DOI - 10.1155/2011/797820

Subject(s) - gammaretrovirus , virology , virus , medicine , chronic fatigue syndrome , leukemia , retrovirus , lymphoma , murine leukemia virus , immunology

Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with human prostate cancer and chronic fatigue syndrome. Since retroviruses cause various cancers, and XMRV replication might be facilitated by HIV-1 co-infection, we asked whether certain patients with HIV-associated lymphomas are infected with XMRV. Analysis of PMBCs and plasma from 26 patients failed to detect XMRV by PCR, ELISA, or Western blot, suggesting a lack of association between XMRV and AIDS-associated lymphomas.

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