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Gypsum‐Catalyzed One‐Pot Synthesis of 3,4‐Dihydropyrimidin‐2(1H) Under Solvent‐Free Conditions
Author(s) -
Taoues Boumoud,
Boudjemaa Boumoud,
Paul Mosset,
Abdelmadjid Debache
Publication year - 2010
Publication title -
journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2090-9063
pISSN - 2090-9071
DOI - 10.1155/2011/780271
Subject(s) - chemistry , catalysis , gypsum , environmentally friendly , organic chemistry , condensation , green chemistry , condensation reaction , biginelli reaction , solvent , ionic liquid , metallurgy , ecology , materials science , physics , biology , thermodynamics
In view of the emerging importance of the green chemistry principles in chemical and pharmaceutical industries, we disclose, herein, a new economic approach producing the biologically active dihydropyrimidinones in good yields using the solventless one-pot Biginelli condensation in the presence of gypsum as an environmental friendly and recycled catalyst.

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