Familial Adenomatous Polyposis—Rendering a Diagnosis Based on Recognition of an Unusual Primary Thyroid Neoplasm | Zendy

David F. Schaeffer | Zendy; Eric M. Yoshida | Zendy; David Owen | Zendy; Kenneth W. Berean | Zendy

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Familial Adenomatous Polyposis—Rendering a Diagnosis Based on Recognition of an Unusual Primary Thyroid Neoplasm

Author(s) -

David F. Schaeffer,

Eric M. Yoshida,

David Owen,

Kenneth W. Berean

Publication year - 2011

Publication title -

case reports in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.2

H-Index - 20

eISSN - 1687-9627

pISSN - 1687-9635

DOI - 10.1155/2011/767610

Subject(s) - familial adenomatous polyposis , medicine , thyroid neoplasm , cribriform , germline mutation , thyroid tumors , pathology , thyroid , neoplasm , germline , thyroid carcinoma , carcinoma , mutation , colorectal cancer , cancer , biochemistry , chemistry , gene

It has been well established in the literature that the cribriform-morular variant of papillary thyroid carcinoma (CMVPTC) has been observed with higher frequency in familial adenomatous polyposis (FAP) patients. In the usual setting, patients with FAP are identified based on their germline mutations and the diagnosis of thyroid neoplasm is made after the FAP diagnosis. We herein report a case in which the recognition of a CMVPTC led to the initial diagnosis of FAP. The histological and clinical features of CMVPTC are reviewed with emphasis on its relationship to FAP.

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