Open AccessOlfactory Neuroblastoma Treated by Endoscopic Surgery Followed by Combined External Beam Radiation and Gamma Knife for Optic Nerve and Chiasm Sparing: A Case Report
Author(s) -
Hansi Z. Jiang,
Ameer L. Elaimy,
Guy C. Jones,
A Mackay,
Robert K. Fairbanks,
Wayne T. Lamoreaux,
John J. Demakas,
Barton S. Cooke,
Christopher M. Lee
Publication year - 2011
Publication title -
case reports in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.2
H-Index - 20
eISSN - 1687-9627
pISSN - 1687-9635
DOI - 10.1155/2011/765645
Subject(s) - medicine , radiosurgery , cribriform plate , radiation therapy , nasal cavity , surgery , ethmoid sinus , cavernous sinus , optic nerve , external beam radiation , cribriform , stage (stratigraphy) , optic chiasm , sinus (botany) , radiology , ophthalmology , carcinoma , pathology , paleontology , botany , biology , genus
We describe the multimodality treatment regimen of a 53-year-old man diagnosed with olfactory neuroblastoma (Kadish stage C) in the right nasal cavity extending into the ethmoid sinus and across the cribriform plate. Endoscopic surgery for tumor resection was followed by a combination of external beam radiotherapy and stereotactic radiosurgery boost with concurrent chemotherapy. The novel combination of dual radiation therapies allowed for the preservation of the nearby optic structures while providing an adequate dosage to a sufficient volume of the afflicted tissue.
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