In Vitro Antimicrobial Susceptibility ofMycobacterium massilienseRecovered from Wound Samples of Patients Submitted to Arthroscopic and Laparoscopic Surgeries

Testing of rapidly growing species of mycobacteria (RGM) against antibacterial agents has been shown to have some clinical utility. This work establishes the MICs of seven antimicrobial agents following the guidelines set forth by the Clinical and Laboratory Standards Institute (CLSI) against eighteen isolates of Mycobacterium massiliense recovered from wound samples of patients submitted to minimally invasive surgery such as arthroscopy and laparoscopy. The isolates showed susceptibility to amikacin (MIC 90 = 4  μ g/mL) and clarithromycin (MIC 90 < 1  μ g/mL) but resistance to ciprofloxacin (MIC 90 > 16  μ g/mL), doxycycline (MIC 90 > 32  μ g/mL), sulfamethoxazole (MIC 90 > 128  μ g/mL), and tobramycin (MIC 90 = 32  μ g/mL), and intermediate profile to cefoxitin (MIC 90 = 64  μ g/mL). Therefore, we suggest that the antimicrobial susceptibilities of any clinically significant RGM isolate should be performed.