A Case of Adalimumab‐Induced Pneumonitis in a 45‐Year‐Old Man with Crohn’s Disease | Zendy

James D. Reid | Zendy; Brian Bressler | Zendy; John C. English | Zendy

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A Case of Adalimumab‐Induced Pneumonitis in a 45‐Year‐Old Man with Crohn’s Disease

Author(s) -

James D. Reid,

Brian Bressler,

John C. English

Publication year - 2011

Publication title -

canadian respiratory journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.675

H-Index - 53

eISSN - 1916-7245

pISSN - 1198-2241

DOI - 10.1155/2011/713821

Subject(s) - adalimumab , medicine , rheumatoid arthritis , crohn's disease , inflammatory bowel disease , disease , monoclonal antibody , lung , monoclonal , pneumonitis , infliximab , necrosis , dermatology , pathology , immunology , antibody

Adalimumab is a human monoclonal antibody against tumour necrosis factor-alpha that has been associated with acute lung toxicity, mainly in patients with rheumatoid arthritis. Descriptions of similar patterns of lung injury in patients treated with adalimumab for inflammatory bowel disease are emerging in the literature. A case involving a 45-year-old man with Crohn's disease who developed a nonbronchiolitis inflammatory nodular pattern of lung injury after starting adalimumab is reported.

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