z-logo
open-access-imgOpen Access
Activity of Cathelicidin Peptides against Simkania negevensis
Author(s) -
Manuela Donati,
Antonietta Di Francesco,
Maria Di Paolo,
N Fiani,
Monica Benincasa,
Renato Gennaro,
Paola Nardini,
Claudio Foschi,
Roberto Cevenini
Publication year - 2011
Publication title -
international journal of peptides
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.239
H-Index - 25
eISSN - 1687-9775
pISSN - 1687-9767
DOI - 10.1155/2011/708710
Subject(s) - cathelicidin , chlamydiae , antimicrobial peptides , antimicrobial , microbiology and biotechnology , biology , chemistry , immunology , chlamydia
The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptides—PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28—proved to be active at very low concentrations (1 to 0.1  μ g/mL), while LL-37 cathelicidin was ineffective even at a concentration of 100  μ g/mL. In comparison to chlamydiae, S. negevensis proved to be more susceptible to the antimicrobial peptides tested.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom