Episcleritis Related to Drug-Induced Lupus Erythematosus following Infliximab Therapy: A Case Report
Author(s) -
Irini Chatziralli,
Evgenia Kaidou,
Alexandros Chatzirallis,
Prodromos Dimitriadis,
Petros Keryttopoulos
Publication year - 2011
Publication title -
case reports in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.2
H-Index - 20
eISSN - 1687-9627
pISSN - 1687-9635
DOI - 10.1155/2011/696285
Subject(s) - medicine , episcleritis , discontinuation , systemic lupus erythematosus , infliximab , drug , dermatology , lupus erythematosus , immunology , tumor necrosis factor alpha , disease , scleritis , pharmacology , antibody , uveitis
Drug-induced lupus erythematosus is defined as a lupus-like syndrome temporally related to continuous drug exposure which resolves after discontinuation of the offending drug. Herein, we describe a patient with distinct clinical manifestations of anti-TNF-associated DILE related to infliximab therapy. The patient exhibited clinical and laboratory findings of lupus-like illnesses as well as ocular disorders, such as episcleritis. The main message is that the symptoms of DILE should not be overlooked, although sometimes other systematic conditions may underlie them. As a result, it is very important for the clinicians to evaluate the symptoms of DILE and manage appropriately these cases.
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