Retrospective Analysis of High-Dose Intrathecal Morphine for Analgesia after Pelvic Surgery | Zendy

Annette Rebel | Zendy; Paul A. Sloan | Zendy; Michael A. Andrykowski | Zendy

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Retrospective Analysis of High-Dose Intrathecal Morphine for Analgesia after Pelvic Surgery

Author(s) -

Annette Rebel,

Paul A. Sloan,

Michael A. Andrykowski

Publication year - 2011

Publication title -

pain research and management

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.702

H-Index - 56

eISSN - 1918-1523

pISSN - 1203-6765

DOI - 10.1155/2011/691712

Subject(s) - medicine , morphine , intrathecal , anesthesia , retrospective cohort study , surgery

The effectiveness of intrathecal opioids (ITOs) for postoperative analgesia has been limited by reduced opioid dosing because of opioid-related side effects, most importantly respiratory depression. To overcome these limitations, high-dose intrathecal morphine was combined with a continuous intravenous (IV) postoperative naloxone infusion. The aim of the present chart analysis was to investigate the safety and efficacy of high-dose ITOs combined with IV naloxone compared with IV opioid analgesia alone.

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