Open AccessPhase Transfer Catalysis Assisted Thorpe Reaction for the Synthesis of 3-Aminothiophene-2-carboxylates
Author(s) -
Rina D. Shah
Publication year - 2010
Publication title -
journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2090-9063
pISSN - 2090-9071
DOI - 10.1155/2011/650501
Subject(s) - catalysis , phase (matter) , chemistry , combinatorial chemistry , organic chemistry , transfer (computing) , computer science , parallel computing
Thorpe cyclization constructing synthetically important methyl or ethyl 3-amino-4-arylthiophene-2-carboxylates has been studied using eco friendly phase transfer catalysis technique. 3-Amino-4-arylthiophene-2-carboxylates have been synthesized from 3-hydroxy-2-arylacrylonitriles and thioglycolates under different solid-liquid phase-transfer conditions
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