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Hopf Bifurcation for a Model of HIV Infection ofCD4+T Cells with Virus Released Delay
Author(s) -
Junyuan Yang,
Xiaoyan Wang,
Xuezhi Li
Publication year - 2011
Publication title -
discrete dynamics in nature and society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.264
H-Index - 39
eISSN - 1607-887X
pISSN - 1026-0226
DOI - 10.1155/2011/649650
Subject(s) - hopf bifurcation , stability (learning theory) , bifurcation , period (music) , virus , human immunodeficiency virus (hiv) , algorithm , computer science , physics , virology , biology , machine learning , quantum mechanics , nonlinear system , acoustics
A viral model of HIV infection of CD4+ T-cells with virus released period is formulated, and the effect of this released period on the stability of the equilibria is investigated. It is shown that the introduction of the viral released period can destabilize the system, and the period solution may arise. The direction and stability of the Hopf bifurcation are also discussed. Numerical simulations are presented to illustrate the results

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