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Lenalidomide-Associated ITP
Author(s) -
Christina I. Herold,
Cristina Gasparetto,
Gowthami M. Arepally
Publication year - 2011
Publication title -
case reports in hematology
Language(s) - English
Resource type - Journals
eISSN - 2090-6560
pISSN - 2090-6579
DOI - 10.1155/2011/638020
Subject(s) - lenalidomide , medicine , multiple myeloma , thalidomide , thrombocytopenic purpura , immune thrombocytopenia , limiting , myelodysplastic syndromes , immune system , immunology , antibody , bone marrow , mechanical engineering , engineering
Lenalidomide is a potent immunomodulatory agent being used increasingly for treatment of hematologic malignancies including multiple myeloma and myelodysplasia. The common toxicities of lenalidomide, including dose-limiting myelosuppression, are well described. However, the immunomodulatory properties of lenalidomide may give rise to unexpected autoimmune complications. Herein, we describe a case of immune thrombocytopenic purpura (ITP) associated with use of lenalidomide.

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