Synthesis and Pharmacological Evaluation of Some Phenylpyrazolo Indoquinoxaline Derivatives | Zendy

C. Sridevi | Zendy; K. Balaji | Zendy; A. Naidu | Zendy

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Synthesis and Pharmacological Evaluation of Some Phenylpyrazolo Indoquinoxaline Derivatives

Author(s) -

C. Sridevi,

K. Balaji,

A. Naidu

Publication year - 2010

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2011/584817

Subject(s) - combinatorial chemistry , computer science , chemistry

Indoloquinoxalin was fused with 2,3 diphenyl quinoxaline by a methylene bridge which was then allowed for acetylation. The acetylated product was made to react with different aromatic aldehydes to give chalcones. Chalcones refluxed with substituted acid hydrazides to afford different indoloquinoxaline pyrazolines. The structure of chalcones and indoloquinoxaline pyrazolines were confirmed by M.P, TLC and spectral data. All the synthesized compounds were screened for their antioxidant, anti-inflammatory and antihistamic activities

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