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3D Winding Number: Theory and Application to Medical Imaging
Author(s) -
Alessandro Becciu,
A. Fuster,
Mark Pottek,
Bart van den Heuvel,
Bart M. ter Haar Romeny,
Hans C. van Assen
Publication year - 2011
Publication title -
international journal of biomedical imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 41
eISSN - 1687-4196
pISSN - 1687-4188
DOI - 10.1155/2011/516942
Subject(s) - computer science , winding number , generalization , scalar (mathematics) , reliability (semiconductor) , artificial intelligence , data mining , topology (electrical circuits) , mathematics , physics , geometry , mathematical analysis , power (physics) , quantum mechanics , combinatorics
We develop a new formulation, mathematically elegant, to detect critical points of 3D scalar images. It is based on a topological number, which is the generalization to three dimensions of the 2D winding number. We illustrate our method by considering three different biomedical applications, namely, detection and counting of ovarian follicles and neuronal cells and estimation of cardiac motion from tagged MR images. Qualitative and quantitative evaluation emphasizes the reliability of the results.

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