Synthesis of β-Amino Carbonyl Compounds via the Iodine-Alumina Catalyzed Three-Component Coupling Reaction under Microwave Irradiation
Author(s) -
Mantu Rajbangshi,
Md. Rumum Rohman,
Icydora Kharkongor,
Hormi Mecadon,
Bekington Myrboh
Publication year - 2011
Publication title -
organic chemistry international
Language(s) - English
Resource type - Journals
eISSN - 2090-2018
pISSN - 2090-200X
DOI - 10.1155/2011/514620
Subject(s) - catalysis , iodine , chemistry , microwave irradiation , microwave , coupling reaction , organic chemistry , carbamate , component (thermodynamics) , coupling (piping) , combinatorial chemistry , photochemistry , materials science , physics , quantum mechanics , metallurgy , thermodynamics
Iodine-alumina was employed as a catalyst in the coupling reactions of aldehydes, enolizable ketones, or 1,3-dicarbonyls with methyl carbamate or aromatic amines under microwave irradiation to afford β-amino carbonyl compounds in good-to-excellent yields. The key features of this environmentally friendly methodology are its operational simplicity, mild reaction conditions, and less reaction time
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