A Comparison between Enriched and Nonenriched Enrollment Randomized Withdrawal Trials of Opioids for Chronic Noncancer Pain | Zendy

Andrea D Furlan | Zendy; Luis Enrique Chaparro | Zendy; Emma Irvin | Zendy; Angela Mailis | Zendy

Open Access

A Comparison between Enriched and Nonenriched Enrollment Randomized Withdrawal Trials of Opioids for Chronic Noncancer Pain

Author(s) -

Andrea D Furlan,

Luis Enrique Chaparro,

Emma Irvin,

Angela Mailis

Publication year - 2011

Publication title -

pain research and management

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.702

H-Index - 56

eISSN - 1918-1523

pISSN - 1203-6765

DOI - 10.1155/2011/465281

Subject(s) - medicine , randomized controlled trial , chronic pain , placebo , subgroup analysis , medline , opioid , meta analysis , physical therapy , alternative medicine , receptor , pathology , political science , law

An enriched enrollment randomized withdrawal (EERW) design excludes potential participants who are nonresponders or who cannot tolerate the experimental drug before random assignment. It is unclear whether EERW design has an influence on the efficacy and safety of opioids for chronic noncancer pain (CNCP).

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