Open AccessMetabolic Profile of Offspring from Diabetic Wistar Rats Treated with Mentha piperita (Peppermint)
Author(s) -
Sandra Maria Barbalho,
Débora Cristina Damasceno,
Ana Paula Machado Spada,
Vanessa Sellis da Silva,
Karla Aparecida Martuchi,
Marie Oshiiwa,
Flávia Maria Vasques Farinazzi-Machado,
Claudemir Gregório Mendes
Publication year - 2011
Publication title -
evidence-based complementary and alternative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.552
H-Index - 90
eISSN - 1741-4288
pISSN - 1741-427X
DOI - 10.1155/2011/430237
Subject(s) - offspring , dyslipidemia , diabetes mellitus , lipid profile , cholesterol , medicine , total cholesterol , streptozotocin , endocrinology , biology , pregnancy , genetics
This study aimed at evaluating glycemia and lipid profile of offspring from diabetic Wistar rats treated with Mentha piperita (peppermint) juice. Male offspring from nondiabetic dams (control group: 10 animals treated with water and 10 treated with peppermint juice) and from dams with streptozotocin-induced severe diabetes (diabetic group: 10 animals treated with water and 10 treated with peppermint juice) were used. They were treated during 30 days, and, after the treatment period, levels of glycemia, triglycerides, total cholesterol, and fractions were analyzed in the adult phase. The offspring from diabetic dams treated with peppermint showed significantly reduced levels of glucose, cholesterol, LDL-c, and triglycerides and significant increase in HDL-c levels. The use of the M. piperita juice has potential as culturally appropriate strategy to aid in the prevention of DM, dyslipidemia, and its complications.
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