Spectrofluorimetric Method for the Estimation of Erlotinib Hydrochloride in Pure and Pharmaceutical Formulations | Zendy

V. Rajesh | Zendy; V. Jagathi | Zendy; K. Sindhuri | Zendy; G. Devala Rao | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Spectrofluorimetric Method for the Estimation of Erlotinib Hydrochloride in Pure and Pharmaceutical Formulations

Author(s) -

V. Rajesh,

V. Jagathi,

K. Sindhuri,

G. Devala Rao

Publication year - 2010

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2011/426452

Subject(s) - erlotinib , excitation wavelength , dosage form , chromatography , methanol , fluorescence , chemistry , materials science , analytical chemistry (journal) , wavelength , organic chemistry , optics , physics , biochemistry , receptor , optoelectronics , epidermal growth factor receptor

A simple and sensitive spectrofluorimetric method has been developed for the estimation of erlotinib hydrochloride in pure and pharmaceutical dosage forms. Erlotinib hydrochloride exhibits maximum fluorescence intensity in methanol and the Beer's law was obeyed in the range of 1-5 µg/mL at an excitation wavelength (λex) of 295 nm and an emission wavelength (λem) of 339 nm. Stability studies with respect to time and temperature were also carried out. The results obtained were in good agreement with the labelled amounts of the marketed formulations. This method has been statistically evaluated and found to be accurate and precise.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research