Micro-RNA Expression and Function in Lymphomas | Zendy

Sukhinder K. Sandhu | Zendy; Carlo M. Croce | Zendy; Ramiro Garzon | Zendy

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Micro-RNA Expression and Function in Lymphomas

Author(s) -

Sukhinder K. Sandhu,

Carlo M. Croce,

Ramiro Garzon

Publication year - 2011

Publication title -

advances in hematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.371

H-Index - 31

eISSN - 1687-9112

pISSN - 1687-9104

DOI - 10.1155/2011/347137

Subject(s) - microrna , function (biology) , disease , medicine , gene expression , pathogenesis , computational biology , expression (computer science) , human disease , gene , bioinformatics , cancer research , biology , genetics , immunology , pathology , computer science , programming language

The recent discovery of microRNAs (miRNAs) has introduced a new layer of complexity to the process of gene regulation. MiRNAs are essential for cellular function, and their dysregulation often results in disease. Study of miRNA expression and function in animal models and human lymphomas has improved our knowledge of the pathogenesis of this heterogeneous disease. In this paper, we attempt to describe the expression of miRNAs and their function in lymphomas and discuss potential miRNA-based therapies in the diagnosis and treatment of lymphomas.

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