Characterization of a Low Pathogenic Avian Influenza Virus (H6N1) Isolated from Turkeys | Zendy

I. Shkoda | Zendy; E. Lapin | Zendy; Ezra Rosenbluth | Zendy; Shimon Perk | Zendy; Z. Geva | Zendy; Inbar Am | Zendy; Irit Davidson | Zendy

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Characterization of a Low Pathogenic Avian Influenza Virus (H6N1) Isolated from Turkeys

Author(s) -

I. Shkoda,

E. Lapin,

Ezra Rosenbluth,

Shimon Perk,

Z. Geva,

Inbar Am,

Irit Davidson

Publication year - 2010

Publication title -

influenza research and treatment

Language(s) - English

Resource type - Journals

eISSN - 2090-1399

pISSN - 2090-1380

DOI - 10.1155/2011/285218

Subject(s) - hemagglutinin (influenza) , influenza a virus subtype h5n1 , virus , biology , virology , hemagglutination assay , pathogenicity , hemagglutination , avian influenza virus , influenza a virus , gene , microbiology and biotechnology , genetics , titer

An avian influenza virus (AIV), A/turkey/Israel/09 subtype H6N1, was isolated from turkey poults exhibiting typical pathology associated with AIV infection. The virus was characterized by RT-PCR using AIV subtype-specific primers and by the haemagglutination inhibition test using AIV subtype-specific antisera. The virus has an intravenous pathogenicity index of 0 and possessed a nucleotide sequence at the cleavage site of the hemagglutinin gene, PQIETR*GLF, associated with avian influenza viruses of low pathogenicity. Unlike the two previous H6N2 isolates originating from domestic ducks and mallard, the A/turkey/Israel/09 (H6N1) was isolated from turkeys. The gene sequences of the A/turkey/Israel/09 (H6N1) virus show divergence from the former Israeli H6 isolates.

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