Microwave Assisted Synthesis and Antimicrobial Evaluation of Schiff Bases of Indole-3-aldehyde | Zendy

Priyanka Kamaria | Zendy; Neha Kawathekar | Zendy; Prerna Chaturvedi | Zendy

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Microwave Assisted Synthesis and Antimicrobial Evaluation of Schiff Bases of Indole-3-aldehyde

Author(s) -

Priyanka Kamaria,

Neha Kawathekar,

Prerna Chaturvedi

Publication year - 2010

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2011/265329

Subject(s) - antimicrobial , aldehyde , gram , indole test , chemistry , schiff base , solvent , proton nmr , strain (injury) , organic chemistry , combinatorial chemistry , microbiology and biotechnology , stereochemistry , bacteria , biology , catalysis , genetics , anatomy

In order to develop new antimicrobial agents, a series of Schiff bases of indole-3-aldehyde were synthesized by microwave assisted synthesis by taking DMF as solvent and evaluated for their antimicrobial activity. All the synthesized compounds were characterized by IR, 1HNMR and mass spectral analysis. All compounds were tested against five gram positive and five gram negative bacterial strains and one fungal strain. All compounds exhibited better activity against gram positive strains than against gram negative strains and the compounds were found more active against S.aureus and B.subtilis

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