Green Urine Discoloration due to Propofol Infusion: A Case Report | Zendy

Nobuki Shioya | Zendy; Yoriko Ishibe | Zendy; Shigehiro Shibata | Zendy; Hideyuki Makabe | Zendy; Shigenori Kan | Zendy; Naoya Matsumoto | Zendy; Gaku Takahashi | Zendy; Yasuhiko Yamada | Zendy; Shigeatsu Endo | Zendy

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Green Urine Discoloration due to Propofol Infusion: A Case Report

Author(s) -

Nobuki Shioya,

Yoriko Ishibe,

Shigehiro Shibata,

Hideyuki Makabe,

Shigenori Kan,

Naoya Matsumoto,

Gaku Takahashi,

Yasuhiko Yamada,

Shigeatsu Endo

Publication year - 2011

Publication title -

case reports in emergency medicine

Language(s) - English

Resource type - Journals

eISSN - 2090-648X

pISSN - 2090-6498

DOI - 10.1155/2011/242514

Subject(s) - propofol , medicine , urine , glucuronidation , enterohepatic circulation , anesthesia , bilirubin , sedation , surgery , gastroenterology , metabolism , chemistry , enzyme , microsome , biochemistry

We present a 19-year-old man who excreted green urine after propofol infusion. The patient was admitted to our hospital for injuries sustained in a traffic accident and underwent surgery. After starting continuous infusion of propofol for postoperative sedation, his urine became dark green. Serum total bilirubin and urine bilirubin were both elevated. We believe that the green discoloration of the urine was caused by propofol infusion and was related to impaired enterohepatic circulation and extrahepatic glucuronidation in the kidneys.

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