Rapid and Significant Reduction in Size of Pituitary Adenoma in Children Treated with Fractionated Stereotactic Radiation Therapy: A Case Report

Radiation treatment in the management of pituitary adenoma in children is still a controversy due to the great concern of late radiation effect. Stereotactic radiation therapy is the modern radiation technique that is more widely applicable in pituitary adenoma because of the ability to give highly conformal radiation to the target organ and to reduce the radiation dose to normal tissue. A 15-year-old boy presented with postradiation therapy recurrence pituitary macroadenoma. His vision was useful only on the left eye. MRI revealed the recurrent macroadenoma with severe invasion of optic apparatus. Since no any other treatment option was to be given to this patient, we decided to reirradiate the patient with conventional fractionated stereotactic radiation. At 3 months of followup, MRI showed that the tumor had an early and significant reduction in size without any sign of toxicity.