Staged Mucosal Advancement Flap versus Staged Fibrin Sealant in the Treatment of Complex Perianal Fistulas | Zendy

S. J. van der Hagen | Zendy; C.G.M.I. Baeten | Zendy; Peter B. Soeters | Zendy; Wim G. van Gemert | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Staged Mucosal Advancement Flap versus Staged Fibrin Sealant in the Treatment of Complex Perianal Fistulas

Author(s) -

S. J. van der Hagen,

C.G.M.I. Baeten,

Peter B. Soeters,

Wim G. van Gemert

Publication year - 2011

Publication title -

gastroenterology research and practice

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.622

H-Index - 45

eISSN - 1687-630X

pISSN - 1687-6121

DOI - 10.1155/2011/186350

Subject(s) - medicine , sealant , fibrin , surgery , fistula , anal fistula , fibrin tissue adhesive , fibrin glue , chemistry , organic chemistry , immunology

Background . In this prospective randomised study, the staged mucosal advancement flap is compared with staged fibrin sealant application in the treatment of perianal fistulas. Methods . All patients with high complex cryptoglandular fistulas were randomised to closure of the internal opening by a mucosal advancement flap (MF) or injection with fibrin sealant (FS) after treatment with setons. Recurrence rate and incontinence disorders were explored. Results . The MF group (5 females and 10 males) with a median age of 51 years and a median followup of 52 months. The FS group (4 females and 11 males) with a median age of 45 years and a median followup of 49 months. Three (20%) patients of the MF group had a recurrent fistula compared to 9 (60%) of the FS group ( P = 0.03). No new continence disorders developed. Conclusion . Staged FS injection has a much lower success rate compared to MF.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research