Open AccessHeteropoly Acid Catalyzed Selective Cyclization of 6-Alkyl-3-propargylmercapto-1,2,4-triazin-5(2H)-one
Author(s) -
Fatemeh Hakim,
Masoumeh Tabatabaee,
Majid Μ. Heravi,
Mina Roshani,
Fatemeh F. Bamoharam
Publication year - 2010
Publication title -
journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2090-9063
pISSN - 2090-9071
DOI - 10.1155/2011/103913
Subject(s) - catalysis , alkyl , chemistry , medicinal chemistry , organic chemistry
Cyclization of 6-alkyl-3-propargylmercapto-1,2,4-triazin-5(2H)-one, derivatives (2) in the presence of Keggin heteropoly acids, H3PW1212O40, H3PMo12O40, H4SiW12O40 and lacunary Keggin structure (K7PMo2W9O40) afforded 3 (3a = 6-dimethyl-7H-thiazolo[2,3-b][1,2,4]-triazin-7-one and 3b=6-ethyl-3-methyl-7H-thiazolo[2,3-b][1,2,4]-triazin-7-one) in high yields and short reaction times
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