Open AccessInfluence of Soy Lecithin Administration on Hypercholesterolemia
Author(s) -
Amouni Mohmoud Mourad,
Eder de Carvalho Pincinato,
Priscila Gava Mazzola,
Maricene Sabha,
Patrícia Moriel
Publication year - 2009
Publication title -
cholesterol
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.876
H-Index - 20
eISSN - 2090-1291
pISSN - 2090-1283
DOI - 10.1155/2010/824813
Subject(s) - lecithin , cholesterol , medicine , endocrinology , capsule , lipoprotein , ldl cholesterol , chemistry , biochemistry , biology , botany
Recent studies suggest that lecithin-rich diet can modify cholesterol homeostasis and hepatic lipoprotein metabolism. Considering the phytotherapeutic impact of lecithin, this work hypothesizes that lecithin administration in hypercholesterolemic patients may reduce cholesterol concentrations by increasing biliary secretion. Total cholesterol and LDL were evaluated after soy lecithin administration in hypercholesterolemic patients. One soy lecithin capsule (500 mg/RP-Sherer) was administrated daily. One-two months before the treatment beginning, blood samples were collected for total lipids and cholesterol fractions analysis. The results showed a reduction of 40.66% and 42.00% in total cholesterol and of 42.05% and 56.15% in LDL cholesterol after treatment for one and two months, respectively. A significant reduction in total cholesterol and LDL-cholesterol concentrations was observed during the first month of treatment, suggesting that the administration of soy lecithin daily may be used as a supplemental treatment in hypercholesterolemia
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