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Surgical Treatment by Partial Petrosectomy for a Middle-Ear Carcinoid with Progressive Extension: A Case Report and Review of the Literature
Author(s) -
Mitsuhiro Aoki,
Keisuke Mizuta,
Natsuko Ueda,
Nansei Yamada,
Yatsuji Ito,
Hiroki Kato,
Yoshinobu Hirose
Publication year - 2010
Publication title -
international journal of otolaryngology
Language(s) - English
Resource type - Journals
eISSN - 1687-921X
pISSN - 1687-9201
DOI - 10.1155/2010/818673
Subject(s) - medicine , synaptophysin , chromogranin a , cytokeratin , middle ear , pathology , surgery , immunohistochemistry
We herein report a 59-year-old male patient with a recurrent carcinoid tumor of the middle ear 7 years after a tympanomastoidectomy. The CT and dynamic MRI demonstrated an extensive tumor close to the carotid artery canal and the jugular bulb, and the tumor was removed by a partial petrosectomy with a transmastoid approach. The histopathological findings revealed a solid and trabecular tumor with cells positive for cytokeratin, chromogranin A, synaptophysin, and CD56. The MIB-1 antibody for the Ki-67 antigen was positive in 6.6% of the tumor cells. The relevant literature is reviewed in regard to the present case.

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