Mediators of Inflammation in Polycystic Ovary Syndrome in Relation to Adiposity | Zendy

Thozhukat Sathyapalan | Zendy; Stephen L. Atkin | Zendy

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Mediators of Inflammation in Polycystic Ovary Syndrome in Relation to Adiposity

Author(s) -

Thozhukat Sathyapalan,

Stephen L. Atkin

Publication year - 2010

Publication title -

mediators of inflammation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.37

H-Index - 97

eISSN - 1466-1861

pISSN - 0962-9351

DOI - 10.1155/2010/758656

Subject(s) - polycystic ovary , obesity , inflammation , endocrine system , medicine , endocrinology , adipose tissue , adipocyte , ovary , insulin resistance , hormone

Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age group and is associated with a higher cardiovascular risk. Obesity, mainly visceral adiposity, is prevalent in patients with PCOS. Obesity is associated with low-grade inflammation and raised inflammatory cytokines, both of which are also described in patients with PCOS. In this paper, the potential relationships between fat distribution, adipocyte dysfunction and, altered inflammatory markers in patients with PCOS have been discussed.

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