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The quinolone resistance-determining regions of gyrA and parC of both quinolone-sensitive and quinolone-resistant Haemophilus parainfluenzae strains were amplified and sequenced. Similar to Haemophilus influenzae, resistance to quinolones in H parainfluenzae is associated with mutations in the quinolone resistance-determining regions of both gyrA and parC. The present study discusses the importance of this finding.

the canadian journal of infectious diseases and medical microbiology/canadian journal of infectious diseases and medical microbiology

Genetic Detection of Quinolone Resistance inHaemophilus parainfluenzae: Mutations in the Quinolone Resistance-Determining Regions ofgyrA andparC