Genetic Detection of Quinolone Resistance inHaemophilus parainfluenzae: Mutations in the Quinolone Resistance-Determining Regions ofgyrA andparC | Zendy

Dennis K. S. Law | Zendy; Michelle Shuel | Zendy; Sadjia Békal | Zendy; Elizabeth Bryce | Zendy; Raymond S. W. Tsang | Zendy

Open Access

Genetic Detection of Quinolone Resistance inHaemophilus parainfluenzae: Mutations in the Quinolone Resistance-Determining Regions ofgyrA andparC

Author(s) -

Dennis K. S. Law,

Michelle Shuel,

Sadjia Békal,

Elizabeth Bryce,

Raymond S. W. Tsang

Publication year - 2010

Publication title -

canadian journal of infectious diseases and medical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.634

H-Index - 38

eISSN - 1918-1493

pISSN - 1712-9532

DOI - 10.1155/2010/525919

Subject(s) - haemophilus parainfluenzae , quinolone , haemophilus , microbiology and biotechnology , haemophilus influenzae , biology , virology , fleroxacin , genetics , ciprofloxacin , bacteria , antibiotics , ofloxacin

The quinolone resistance-determining regions of gyrA and parC of both quinolone-sensitive and quinolone-resistant Haemophilus parainfluenzae strains were amplified and sequenced. Similar to Haemophilus influenzae, resistance to quinolones in H parainfluenzae is associated with mutations in the quinolone resistance-determining regions of both gyrA and parC. The present study discusses the importance of this finding.

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