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The Rate of Prescribing Gastrointestinal Prophylaxis with Either a Proton Pump Inhibitor Or an H2-Receptor Antagonist in Nova Scotia Seniors Starting Nonsteroidal Anti-Inflammatory Drug Therapy
Author(s) -
Bogdan Superceanu,
Sander Veldhuyzen van Zanten,
Chris Skedgel,
Michael Shepherd,
Ingrid Sketris
Publication year - 2010
Publication title -
canadian journal of gastroenterology
Language(s) - English
Resource type - Journals
eISSN - 1916-7237
pISSN - 0835-7900
DOI - 10.1155/2010/397610
Subject(s) - medicine , nova scotia , medical prescription , proton pump inhibitor , cohort , nonsteroidal , drug , gastroenterology , pharmacology , archaeology , history
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used agents that can cause serious gastrointestinal (GI) side effects. For patients at increased risk of NSAID-related GI complications, prophylaxis with either a nonselective NSAID plus gastroprotective agent (GPA) or, alternatively, therapy with a cyclooxygenase-2 selective inhibitor with or without a GPA such as a proton pump inhibitor (PPI), is recommended.

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