Synthesis of Thienopyrimidines and their Antipsychotic Activity
Author(s) -
Chanchal Sharma,
Swapnil G. Yerande,
Rajashree S. Chavan,
A. V. Bhosale
Publication year - 2009
Publication title -
journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2090-9063
pISSN - 2090-9071
DOI - 10.1155/2010/369141
Subject(s) - antipsychotic , psychology , pharmacology , medicine , schizophrenia (object oriented programming) , psychiatry
A series of thienopyrimidines and related heterocycles were synthesized by refluxing related imidoyl chloride with primary and secondary amines under microwave irradiation and classical heating. The imidoyl chlorides were synthesized from corresponding cyclic imides with phosphorus oxychlorides under microwave irradiation and classical heating. The structures of the compounds were confirmed by FT-IR, NMR. The synthesized compounds were screened for anti psychotic activity.
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