Ceftobiprole: First Reported Experience in Osteomyelitis | Zendy

Ashlee MacDonald | Zendy; G Dow | Zendy

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Ceftobiprole: First Reported Experience in Osteomyelitis

Author(s) -

Ashlee MacDonald,

G Dow

Publication year - 2010

Publication title -

canadian journal of infectious diseases and medical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.634

H-Index - 38

eISSN - 1918-1493

pISSN - 1712-9532

DOI - 10.1155/2010/296760

Subject(s) - medicine , septic arthritis , osteomyelitis , forefoot , staphylococcus aureus , vancomycin , surgery , diabetic foot , arthritis , antibiotics , intravenous antibiotics , diabetes mellitus , complication , endocrinology , biology , bacteria , microbiology and biotechnology , genetics

A 74-year-old man with long-standing diabetes presented with advanced infection of the right forefoot associated with septic arthritis and osteomyelitis involving the second and third metatarsophalangeal joints. Polymicrobial infection, which included methicillin-resistant Staphylococcus aureus, was documented. First-line antibiotic therapy, which included vancomycin, was not tolerated. A durable cure was obtained following a six-week course of intravenous ceftobiprole medocaril combined with local surgery. The present report is the first to administer intravenous ceftobiprole medocaril to a patient with methicillin-resistant S aureus-associated septic arthritis and osteomyelitis.

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