Complexation and Antimicrobial Studies of Some Divalent Metal Chelates
Author(s) -
Suparna Ghosh,
Suman Malik
Publication year - 2009
Publication title -
journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2090-9063
pISSN - 2090-9071
DOI - 10.1155/2010/252075
Subject(s) - chelation , molar conductivity , ligand (biochemistry) , metal , stoichiometry , chemistry , divalent , conductivity , stability constants of complexes , inorganic chemistry , divalent metal , organic chemistry , biochemistry , receptor , aqueous solution
Metal chelates of Ni(II) and Cu(II) with the ligand 5-acetamido-1,3,4-thiadiazole-2-sulphonamide have been synthesized. The isolated compounds have been characterized by elemental analysis, molar conductivity, magnetic moment, electronic and IR spectral studies. The analytical data reflects the metal to ligand stoichiometry to be 1: 2. The conductivity data of the complexes also suggests their non-electrolytic nature. The stability constants and free energy change for the complexes have been calculated.. Ligand and their complexes have been screened for their biological activity and the data show good activity of these complexes and ligands
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