Ghrelin in Diabetes and Metabolic Syndrome | Zendy

Leena Pulkkinen | Zendy; Olavi Ukkola | Zendy; Marjukka Kolehmainen | Zendy; Matti Uusitupa | Zendy

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Ghrelin in Diabetes and Metabolic Syndrome

Author(s) -

Leena Pulkkinen,

Olavi Ukkola,

Marjukka Kolehmainen,

Matti Uusitupa

Publication year - 2010

Publication title -

international journal of peptides

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.239

H-Index - 25

eISSN - 1687-9775

pISSN - 1687-9767

DOI - 10.1155/2010/248948

Subject(s) - ghrelin , obesity , metabolic syndrome , type 2 diabetes , medicine , diabetes mellitus , disease , bioinformatics , endocrinology , appetite , biology , hormone

Metabolic syndrome is a cluster of related risk factors for cardiovascular disease, type 2 diabetes and liver disease. Obesity, which has become a global public health problem, is one of the major risk factors for development of metabolic syndrome and type 2 diabetes. Obesity is a complex disease, caused by the interplay between environmental and genetic factors. Ghrelin is one of the circulating peptides, which stimulates appetite and regulates energy balance, and thus is one of the candidate genes for obesity and T2DM. During the last years both basic research and genetic association studies have revealed association between the ghrelin gene and obesity, metabolic syndrome or type 2 diabetes.

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