English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Understanding cellular interactions with material surfaces at the micro- and nanometer scale isessential for the development of the next generation of biomaterials. Several techniques have beenused to create micro- and nanopatterned surfaces as a means of studying cellular interactions with asurface. Herein, we report the novel use of interference lithography to create a large (4 cm2) array of 33 nm deep channels in a gold surface, to expose an antireflective coating on a silicon wafer at the bottomof the gold channels. The fabricated pores had a diameter of 140–350 nm separated by an average pitchof 304–750 nm, depending on the fabrication conditions. The gold surface was treated with 2-(2-(2-(11-mercaptoundecyloxy)ethoxy)ethoxy)ethanol to create protein-resistant areas. Fibronectin wasselectively adsorbed onto the exposed antireflective coating creating nanometer-scale cell adhesivedomains. A murine osteoblast cell line (MC3T3-E1) was seeded onto the surfaces and was shown toattach to the fibronectin domains and spread across the material surface

Large-Scale Protein Arrays Generated with Interferometric Lithography for Spatial Control of Cell-Material Interactions