Aspirin Resistance | Zendy

Khaled Mansour | Zendy; Alì Taher | Zendy; Khaled M. Musallam | Zendy; Samir Alam | Zendy

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Aspirin Resistance

Author(s) -

Khaled Mansour,

Alì Taher,

Khaled M. Musallam,

Samir Alam

Publication year - 2009

Publication title -

advances in hematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.371

H-Index - 31

eISSN - 1687-9112

pISSN - 1687-9104

DOI - 10.1155/2009/937352

Subject(s) - medicine , intensive care medicine , aspirin , dosing , adverse effect , warrant , mechanism (biology) , pharmacology , philosophy , epistemology , financial economics , economics

The development of adverse cardiovascular events despite aspirin use has established an interest in a possible resistance to the drug. Several definitions have been set and various laboratory testing modalities are available. This has led to a wide range of prevalence reports in different clinical entities. The etiologic mechanism has been related to clinical, genetic, and other miscellaneous factors. The clinical implications of this phenomenon are significant and warrant concern. Management strategies are currently limited to dosing alteration and introduction of other anitplatelet agents. However, these measures have not met the expected efficacy or safety.

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