Helicobacter pylori: Determinant and Markers of Virulence | Zendy

Maria Teresa Mascellino | Zendy; M. Margani | Zendy; Alessandra Oliva | Zendy

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Helicobacter pylori: Determinant and Markers of Virulence

Author(s) -

Maria Teresa Mascellino,

M. Margani,

Alessandra Oliva

Publication year - 2009

Publication title -

disease markers

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.912

H-Index - 66

eISSN - 1875-8630

pISSN - 0278-0240

DOI - 10.1155/2009/863493

Subject(s) - virulence , helicobacter pylori , biology , serology , multiplex polymerase chain reaction , multiplex , helicobacter , microbiology and biotechnology , immunology , polymerase chain reaction , genetics , gene , antibody

In this review, we examine the main virulence determinants in Helicobacter pylori ( Hp ) strains and the correlation between these and the different diseases following Hp infections. We also discuss the host response to Hp and the implications and advantages of the development of non-invasive pre-endoscopy screening of molecular and serological markers associated with Hp virulence and disease progression putting an emphasis on new screening techniques such as the Luminex – X multi analytes profiling technology and the multiplex PCR.

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