Bioinorganic Relevance of Some Cobalt(II) Complexes with Thiophene-2-glyoxal Derived Schiff Bases | Zendy

Prashant Singh | Zendy; Shanu Das | Zendy; Rajesh Dhakarey | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Bioinorganic Relevance of Some Cobalt(II) Complexes with Thiophene-2-glyoxal Derived Schiff Bases

Author(s) -

Prashant Singh,

Shanu Das,

Rajesh Dhakarey

Publication year - 2008

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2009/801345

Subject(s) - chemistry , ligand (biochemistry) , pyridine , cobalt , proton nmr , glyoxal , metal , thio , octahedron , nmr spectra database , medicinal chemistry , crystallography , stereochemistry , inorganic chemistry , organic chemistry , spectral line , crystal structure , astronomy , biochemistry , receptor , physics

Complexes of Co(II) with two new Schiff bases TEAB (2-hydroxy-4- {(2-oxo-2-(thiophen-2-yl)ethylidene)amino}benzoic acid) and TEPC ( N-(2-oxo- 2-(thiophen-2-yl)ethylidene)pyridine-3-carboxamide) have been synthesized and characterized with the help of elemental analysis, magnetic, mass, 1H-NMR, 13 C-NMR, IR and electronic spectral data. IR spectra manifest the coordination of the ligand to the metal ion through the carbonyl oxygen, azomethine nitrogen and thienyl sulphur atoms. With the help of electronic spectral data various ligand field parameters were also calculated. All these studies reveal the distorted octahedral Co(II) complexes. Synthesized compounds have also been screened against some micro organisms viz , Escherichia coli, Proteus vulgaris, Aspergillus niger and Aspergillus flavus with the help of 'filter paper disc' technique. It has been observed that the antimicrobial activities of metal complexes are higher than that of the free ligand.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research