UV Spectrophotometric Estimation of Acipimox inBulk and Capsule Dosage Form | Zendy

A. Elphine Prabahar | Zendy; Thangabalan Boovizhikannan | Zendy; R. Kalaichelvi | Zendy; Palanirajan Vijayaraj Kumar | Zendy

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UV Spectrophotometric Estimation of Acipimox inBulk and Capsule Dosage Form

Author(s) -

A. Elphine Prabahar,

Thangabalan Boovizhikannan,

R. Kalaichelvi,

Palanirajan Vijayaraj Kumar

Publication year - 2009

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2009/790531

Subject(s) - capsule , dosage form , chromatography , chemistry , traditional medicine , mathematics , medicine , biology , botany

A new simple, rapid, accurate, sensitive and precise spectrophotometric method in ultra violet region has been developed for determination of acipimox (ACX) in bulk and capsule dosage form. Acipimox exhibited maximum absorbance at 231 nm with apparent molar absorptivity of 1.5104 × 104 in distilled water. Beer’s law was found to be obeyed in the concentration range 1-10 μg mL-1. Correlation coefficient was found to be 0.9998. The developed method was validated respect to linearity, precision, accuracy. The proposed method is useful for the routine estimation of ACX in bulk and capsule dosage form.

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