Cronkhite-Canada Syndrome: A Case Report and Review of Literature | Zendy

Kevin T. Kao | Zendy; Jitesh K. Patel | Zendy; Vijayamalini Pampati | Zendy

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Cronkhite-Canada Syndrome: A Case Report and Review of Literature

Author(s) -

Kevin T. Kao,

Jitesh K. Patel,

Vijayamalini Pampati

Publication year - 2009

Publication title -

gastroenterology research and practice

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.622

H-Index - 45

eISSN - 1687-630X

pISSN - 1687-6121

DOI - 10.1155/2009/619378

Subject(s) - medicine , etiology , diarrhea , dermatology , hyperpigmentation , abdominal pain , weight loss , family history , rare disease , disease , surgery , obesity

Cronkhite-Canada syndrome (CCS) is a rare syndrome first described in 1955. (1) Since then, 400 cases worldwide have been reported in the literature. The disease is characterized by diffuse gastrointestinal polyposis, dystrophic changes of the fingernails, alopecia, cutaneous hyperpigmentation, diarrhea, weight loss, and abdominal pain. (2) The etiology is currently unknown, but an autoimmune process is suspected. The workup is based on history and physical followed by imaging and endoscopy with biopsy to confirm gastrointestinal polyposis. The goal of treatment focuses on symptomatic management of the patient and nutritional support.

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