English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Organotin(IV) complexes with o- or p-hydroxybenzoic acids (o-H 2 BZA or p-H 2 BZA) of formulae [R 2 Sn(HL) 2 ] (where H 2 L = o-H 2 BZA and R = Me- ( 1 ),  n -Bu- ( 2 )); [R 3 Sn(HL)] (where H 2 L = o-H 2 BZA and R =  n -Bu- ( 3 ), Ph- ( 4 ) or H 2 L = p-H 2 BZA and R =  n -Bu- ( 5 ), Ph- ( 6 )) were synthesized by reacting a methanolic solution of di- and triorganotin(IV) compounds with an aqueous solution of the ligand (o-H 2 BZA or p-H 2 BZA) containing equimolar amounts of potassium hydroxide. The complexes were characterized by elemental analysis, FT-IR, Far-IR, TGA-DTA, FT-Raman, Mössbauer spectroscopy,  1 H,  119 Sn-NMR, UV/Vis spectroscopy, and Mass spectroscopy. The X-ray crystal structures of complexes  1  and  2  have also been determined. Finally, the influence of these complexes  1–6  upon the catalytic peroxidation of linoleic acid to hydroperoxylinoleic acid by the enzyme lipoxygenase (LOX) was kinetically studied and the results showed that triorganotin(IV) complex  6  has the lowest IC 50  value. Also complexes  1–6  were studied for their in vitro cytotoxicity against sarcoma cancer cells (mesenchymal tissue) from the Wistar rat, and the results showed that the complexes have high activity against these cell lines with triphenyltin((IV) complex  4  to be the most active one.

Synthesis, Characterization, and Biological Studies of Organotin(IV) Derivatives with o- or p-hydroxybenzoic Acids