Characteristics of Community-Associated Methicillin-ResistantStaphylococcus aureus(CA-MRSA) Strains Isolated from Skin and Soft-Tissue Infections in Uruguay | Zendy

Lorena Pardo | Zendy; Virginia Machado | Zendy; Marta Mollerach | Zendy; María Inés Mota | Zendy; Lorena Tuchscherr | Zendy; Pilar Gadea | Zendy; Noella Gardella | Zendy; Daniel O. Sordelli | Zendy; Magdalena Vola | Zendy; Felipé Schelotto | Zendy; Gustavo Varela | Zendy

Open Access

Characteristics of Community-Associated Methicillin-ResistantStaphylococcus aureus(CA-MRSA) Strains Isolated from Skin and Soft-Tissue Infections in Uruguay

Author(s) -

Lorena Pardo,

Virginia Machado,

Marta Mollerach,

María Inés Mota,

Lorena Tuchscherr,

Pilar Gadea,

Noella Gardella,

Daniel O. Sordelli,

Magdalena Vola,

Felipé Schelotto,

Gustavo Varela

Publication year - 2009

Publication title -

international journal of microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 40

eISSN - 1687-9198

pISSN - 1687-918X

DOI - 10.1155/2009/472126

Subject(s) - leukocidin , pulsed field gel electrophoresis , microbiology and biotechnology , staphylococcus aureus , serotype , methicillin resistant staphylococcus aureus , staphylococcal skin infections , biology , genotype , panton–valentine leukocidin , virology , bacteria , gene , genetics

We analyzed 90 nonduplicates community-associated methicillin-resistant S. aureus (CA-MRSA) strains isolated from skin and soft-tissue infections. All strains were mecA positive. Twenty-four of the 90 strains showed inducible macrolide-lincosamide-streptogramin B resistance. All strains produced α -toxin; 96% and 100% of them displayed positive results for lukS-F and cna genes, respectively. Eigthy-five strains expressed capsular polysaccharide serotype 8. Six different pulsotypes were discriminated by pulsed-field gel electrophoresis (PFGE) and three predominant groups of CA-MRSA strains (1, 2, and 4) were identified, in agreement with phenotypic and genotypic characteristics. Strains of group 1 (pulsotype A, CP8+, and Panton-Valentine leukocidin (PVL)+) were the most frequently recovered and exhibited a PFGE band pattern identical to other CA-MRSA strains previously isolated in Uruguay and Brazil. Three years after the first local CA-MRSA report, these strains are still producing skin and soft-tissue infections demonstrating the stability over time of this community-associated emerging pathogen.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research