A Near‐Fatal Infection with Oseltamivir‐Resistant Seasonal Influenza A in a Previously Healthy Child: Case Report | Zendy

Jesse Papenburg | Zendy; Christos Karatzios | Zendy; Yan Li | Zendy; Nathalie Bastien | Zendy; Makeda Semret | Zendy; Dorothy Moore | Zendy

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A Near‐Fatal Infection with Oseltamivir‐Resistant Seasonal Influenza A in a Previously Healthy Child: Case Report

Author(s) -

Jesse Papenburg,

Christos Karatzios,

Yan Li,

Nathalie Bastien,

Makeda Semret,

Dorothy Moore

Publication year - 2009

Publication title -

canadian journal of infectious diseases and medical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.634

H-Index - 38

eISSN - 1918-1493

pISSN - 1712-9532

DOI - 10.1155/2009/424093

Subject(s) - oseltamivir , amantadine , medicine , epidemiology , seasonal influenza , pediatrics , virology , disease , immunology , covid-19 , infectious disease (medical specialty)

A case of near-fatal oseltamivir-resistant seasonal influenza A infection in a previously healthy four-year-old boy is reported. This case highlights three important points for physicians: oseltamivir-resistant influenza A (H1N1) has recently emerged in North America; contrary to previously held beliefs, such strains are capable of causing severe disease in healthy children; and given this change in epidemiology, clinicians caring for children with severe seasonal influenza A infection should consider empiric dual therapy with oseltamivir and amantadine.

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