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Synthesis and Antimicrobial Activity ofSome New 2‐Substituted Benzothiazole Derivatives
Author(s) -
B. Rajeeva,
N. Srinivasulu,
S. M. Shantakumar
Publication year - 2009
Publication title -
journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2090-9063
pISSN - 2090-9071
DOI - 10.1155/2009/404596
Subject(s) - chemistry , benzothiazole , antimicrobial , aryl , proton nmr , chloride , mass spectrum , oxadiazole , combinatorial chemistry , organic chemistry , medicinal chemistry , stereochemistry , alkyl , ion
Some new 2-(5-substituted-1,3,4-oxadiazole-2-yl)-1,3- benzothiazole (3a-j) were synthesized by refluxing benzothiazolyl carboxyhydrazide with different aryl acids in phosphoryl chloride. Structures of the synthesized compounds were established on the basis of 1H NMR and Mass spectral data. The anti microbial activity of the synthesized compounds was evaluated by disc diffusion method.

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