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Antimicrobial Evaluation and Synthesis of Some Phenylpyrazolo benzothiazolo quinoxaline Derivatives
Author(s) -
C. Sridevi,
K. Balaji,
A. Naidu,
R. Sudhakaran
Publication year - 2009
Publication title -
journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2090-9063
pISSN - 2090-9071
DOI - 10.1155/2009/324358
Subject(s) - quinoxaline , chemistry , antimicrobial , chalcone , acetylation , organic chemistry , combinatorial chemistry , biochemistry , gene
2,3-Diphenyl quinoxaline (SI) was fused with 2-amino benzothiazoles (SII) by a methylene bridge, which was then allowed for acetylation. The acetylated product (SIV) was made to react with different aromatic aldehydes to give chalcones (SV1-SV5). Chalcones refluxed with substituted acid hydrazides to afford different phenyl pyrazolo benzothiazolo quinoxaline derivatives (SVI1-SVI15). The structure of chalcones and phenyl pyrazolo benzothiazolo quinoxaline derivatives were confirmed by M.P, TLC and spectral data. All the synthesized compounds were screened for their antimicrobial activities

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