Low-Molecular-Weight Heparin Use in a Case of Noncardiogenic Multifocal Perinatal Thromboembolic Stroke | Zendy

Matthew A. Saxonhouse | Zendy; Daniel Tarquinio | Zendy; Paul R. Carney | Zendy; Jeff Bennett | Zendy; Amy D. Smith | Zendy; Stephen P. Hunger | Zendy; James D. Geyer | Zendy

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Low-Molecular-Weight Heparin Use in a Case of Noncardiogenic Multifocal Perinatal Thromboembolic Stroke

Author(s) -

Matthew A. Saxonhouse,

Daniel Tarquinio,

Paul R. Carney,

Jeff Bennett,

Amy D. Smith,

Stephen P. Hunger,

James D. Geyer

Publication year - 2009

Publication title -

advances in hematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.371

H-Index - 31

eISSN - 1687-9112

pISSN - 1687-9104

DOI - 10.1155/2009/153643

Subject(s) - medicine , heparin , thrombophilia , stroke (engine) , low molecular weight heparin , thromboembolic stroke , intensive care medicine , pediatrics , surgery , thrombosis , cardiology , mechanical engineering , engineering , atrial fibrillation

A full-term neonate suffered multifocal cerebral infarctions due to multiple large vessel thrombi. Thrombophilia and cardiovascular assessments were negative, but due to the severity of the lesions and the concern for expansion of the thrombi or future embolic events, treatment with low-molecular-weight heparin (LMWH) was initiated. No complications from treatment were experienced. We present this severe case in order to highlight difficult management decisions for newborns with multifocal perinatal thromboembolic stroke and to stress the need for further practice guidelines and research in this area.

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